(Z)-5-Benzenecarbothioyl-1,11-dimethyl-6-phenyl-5H-dibenzo[d,f][1,3]diazepine
نویسندگان
چکیده
The seven-membered ring in the title compound, C(28)H(22)N(2)S, has a two-coordinate N atom as well as a three-coordinate N atom. The ring adopts a boat-shaped conformation with two C atoms of one methyl-phenyl ring as the stern and the three-coordinate N atom as the prow. The N,N-dimethyl-ethane-thio-amide fragment is nearly planar (r.m.s. deviation = 0.049 Å); the phenyl ring of the benzene-carbothioyl unit connected to the three-coordinate N atom is aligned at 83.72 (4)° with respect to the mean plane of this fragment. Weak inter-molecular C-H⋯S hydrogen bonding is present in the crystal structure.
منابع مشابه
N-(5-Nitropyridin-2-yl)-5H-dibenzo[d,f][1,3]diazepine-6-carboxamide
The title compound, C(19)H(13)N(5)O(3), can be obtained from the corresponding α-amido-α-amino-nitrone in a reaction with biphenyl-2,2'-diamine. The amido-amidine core has distinctive geometrical parameters including: an outstandingly long Csp(2)-Csp(2) single bond of 1.5276 (13) Å and an amidine N-C-N angle of 130.55 (9)°. Intra-molecular N-H⋯O, N-H⋯N and C-H⋯O hydrogen bonds occur. In the cry...
متن کاملAnticonvulsant Activities of 7-phenyl-5H-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine and 7-phenyl-5H-thiazolo[5,4-e][1,3,4]triazolo[5,1-c] pyrrolo[1,2-a][1,4]diazepines
Anticonvulsant activity of 7-phenyl-5H-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine (5) and 7-phenyl-5H-thiazolo[5,4-e][1,3,4]triazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepines (6a-d) was measured against pentylenetetrazole (PTZ)-induced seizures in mice. Intraperitoneal injections of different doses (12.5, 25 and 50 mg/kg, i.p.) of test compounds decreased PTZ-induced seizure...
متن کاملAnticonvulsant Activities of 7-phenyl-5H-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine and 7-phenyl-5H-thiazolo[5,4-e][1,3,4]triazolo[5,1-c] pyrrolo[1,2-a][1,4]diazepines
Anticonvulsant activity of 7-phenyl-5H-thiazolo[5,4-e][1,2,3,4]tetrazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepine (5) and 7-phenyl-5H-thiazolo[5,4-e][1,3,4]triazolo[5,1-c]pyrrolo[1,2-a][1,4]diazepines (6a-d) was measured against pentylenetetrazole (PTZ)-induced seizures in mice. Intraperitoneal injections of different doses (12.5, 25 and 50 mg/kg, i.p.) of test compounds decreased PTZ-induced seizure...
متن کاملSynthesis, Characterization and Anti-Breast Cancer Activity of New 4-Aminoantipyrine-Based Heterocycles
4-Aminoantipyrine was utilized as key intermediate for the synthesis of pyrazolone derivatives bearing biologically active moieties. The newly synthesized compounds were characterized by IR, 1H- and 13C-NMR spectral and microanalytical studies. The compounds were screened as anticancer agents against a human tumor breast cancer cell line MCF7, and the results showed that (Z)-4-((3-amino-5-imino...
متن کامل1-Ethoxymethyl-5-methyl-9-phenyl-6,7,8,9-tetrahydro-1H-pyrimido[4,5-b][1,4]diazepine-2,4(3H,5H)-dione
The title compound, C(17)H(22)N(4)O(3), comprises a 1,4-diazepine ring in a twist-boat conformation fused to a pyrimidine ring. The dihedral angle between the pyrimidine and phenyl rings is 80.8 (1)°. The crystal packing features N-H⋯O and C-H⋯O hydrogen bonds.
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
عنوان ژورنال:
دوره 67 شماره
صفحات -
تاریخ انتشار 2011